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Tinea Barbae

Tinea barbae is a fungal infection of the hair follicles of the beard and mustache area. It is typically caused by dermatophytes, such as Trichophyton species. Our company stands out in infectious diseases like tinea barbae by offering unparalleled one-stop integrated services tailored to researchers and scientists in this domain.

Overview of Tinea Barbae

Tinea barbae is a superficial fungal infection that affects the skin, hair, and hair follicles, primarily caused by dermatophytes. While superficial fungal infections are common globally, tinea barbae remains relatively uncommon, with only a limited number of reported cases since its discovery in 1842. The condition is predominantly observed in adult men and is characterized by symptoms such as redness, itching, pustules, and crusting in the affected area.

Macroscopic appearance of Trichophyton mentagrophytes.Fig.1 Trichophyton mentagrophytes complex. (Walkty, A., et al., 2020)

Pathogenesis of Tinea Barbae

Tinea barbae are typically transmitted to humans through direct contact with infected individuals (anthropophilic), soil (geophilic), or infected animals (zoophilic). Among the various causative organisms, Trichophyton species, including Trichophyton verrucosum, Trichophyton mentagrophytes, and Trichophyton rubrum, are commonly implicated in tinea barbae cases. The infection process begins with the spores of these dermatophytes attaching to keratinized tissue, germinating, and producing hyphae that spread into the deeper layers of the skin.

Histopathology of individuals with tinea barbae.Fig.2 Histopathology of a skin biopsy specimen. (Singh, S., et al., 2017)

Therapeutic Development for Tinea Barbae

Therapy for tinea barbae typically involves the use of antifungal drugs, which can be administered topically or orally based on the severity of the infection. Antifungal agents that can be used to treat tinea barbae include:

  • Terbinafine
  • Griseofulvin
  • Ketoconazole
  • Fluconazole
  • Fosravuconazole
  • Others

Our Services

Leveraging our company's state-of-the-art infectious disease model and platform for vaccine and therapeutic advancement, we offer a complete array of solutions. Our integrated services encompass access to cutting-edge laboratory facilities, a diverse range of high-quality research materials, expert consultation from seasoned professionals in the field, and personalized support throughout the research journey.

Vaccine Development Platforms

Therapeutic Development Platforms

Infectious Disease Models

Research on tinea barbae often relies on animal models to study the pathogenesis of the fungal infection and test potential therapeutics. Our company can provide various infectious disease models to help researchers study the disease progression, immune response, and therapy efficacy in a controlled setting.

Infectious disease models.

Researchers can infect animals with tinea barbae-causing fungi to observe the infection's development, and immune response, and assess the effectiveness of antifungal therapeutics.

Optional Models: A mouse model of Trichophyton mentagrophytes infection, etc.

Our dedication to achieving excellence, fostering innovation, and ensuring customer satisfaction establishes us as the preferred partner for researchers and scientists working to combat infectious diseases and make a positive impact. If you are interested in our services, we encourage you to reach out to us for more information.

References

  1. Walkty, Andrew et al. "Tinea barbae presenting as a kerion." Postgraduate medical journal 96.1137 (2020): 441.
  2. Kuruvella, Trinath. and Shivlal Pandey. "Tinea Barbae." StatPearls Publishing (2023).
  3. Singh, Sanjay et al. "Tinea barbae presenting as kerion." Indian journal of dermatology, venereology and leprology 83.6 (2017): 741.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.