In vitro models play a pivotal role in the comprehensive study of infectious diseases. At our company, we have a strong emphasis on developing advanced in vitro models specifically designed for infectious diseases. Collaborating with us, you will gain access to exceptional in vitro models to study pathogen-host interactions, host responses, and evaluate potential therapeutics.
Introduction to In Vitro Models of Infectious Diseases
In vitro models of infectious diseases refer to laboratory systems that mimic the complex interactions between pathogens and host cells outside of a living organism. These models allow researchers to study the molecular and cellular processes involved in infection, replication, immune response, and pathogenesis. By recreating specific aspects of the infection process, in vitro models provide a controlled environment for studying the disease mechanisms and testing potential therapeutics.
Fig. 1 Advanced in vitro models used in research of infectious disease. (Yi H G, et al., 2021)
Typical In Vitro Models of Infectious Diseases
Cell-based Models
Cell-based models serve as fundamental tools for studying infectious diseases. By culturing specific cell types susceptible to infection, researchers can acquire valuable knowledge about the processes involved in pathogen entry, replication, and the immune responses of the host. These models provide a simplified yet powerful representation of host-pathogen interactions.
Organoid Models
Organoid models are three-dimensional cell cultures that are generated from either stem cells or tissue-specific cells. These three-dimensional structures can self-organize and recapitulate the structure and function of specific organs or tissues, thereby providing a higher level of complexity and physiological relevance.
Our Services
In vitro models have revolutionized the study of infectious diseases. With a team of highly skilled professionals and extensive expertise, we are committed to developing cutting-edge in vitro models specifically designed for studying infectious diseases. Our primary objective is to provide these advanced in vitro models to expedite the process of discovering and developing therapeutics for various infectious diseases.
Types of In Vitro Models
Cell-based Models
- Primary cells
- Immortalized cell lines
- Induced pluripotent stem cells (iPSC)
- And More
Organoid Models
- Adult stem cell (ASC) source
- Embryonic stem cell (ESC) source
- Patient-derived organoid (POD)
- And More
Workflow of Cell-based Model Development
Cell Selection
Cell Culture
Experimental Design
Infection Operation
Functional Assays
Validation and Optimization
Workflow of Organoid Model Development
Stem Cell Source Selection
Stem Cell Culture
Inducing Organoid Formation
Experimental Design and Infection
Functional Assays
Validation and Optimization
Questions & Answer
Q: What information do you need to provide for in vitro model development services?
A: We need information about your target infectious disease or pathogen, research goals, cell types, culture conditions, test indicators, timeline, budget, etc.
Q: For which infectious diseases can we develop in vitro models?
A: We can provide in vitro model development services for various types of infections, including bacteria, viruses, parasites, fungi, and prions.
Q: What is the cycle and price of in vitro model development services?
A: The timelines and fees for our services are subject to variation based on the complexity of the project. We are able to offer a comprehensive quote tailored to your specific requirements.
Our company is dedicated to unlocking the complexity of infectious diseases and accelerating drug development through developing exceptional in vitro models. If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
References
- Yi H G, Kim H, Kwon J, et al. Application of 3D bioprinting in the prevention and the therapy for human diseases[J]. Signal Transduction and Targeted Therapy, 2021, 6(1): 177.
- Benam K H, Dauth S, Hassell B, et al. Engineered in vitro disease models[J]. Annual Review of Pathology: Mechanisms of Disease, 2015, 10(1): 195-262.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
