In the field of infectious disease diagnostics, the development of accurate and reliable diagnostic tests is crucial for effective disease prevention and therapy development. Our company is dedicated to providing cutting-edge diagnostics development services to address the challenges posed by infectious diseases.
Diagnostics Development for Infectious Diseases
- The Need for Effective Diagnostics
Infectious diseases pose a significant global health burden, and their timely diagnosis is essential for appropriate therapeutic and disease control. Traditional diagnostic methods, such as culture and microscopy, have limitations in terms of speed, sensitivity, and specificity. To overcome these challenges, the development of advanced diagnostics for infectious diseases is crucial.
- Companion and Complementary Diagnostics
Companion diagnostics (CDx) and complementary diagnostics (cDx) play a vital role in guiding therapeutic decisions for infectious diseases. Companion diagnostics tests are designed to identify specific biomarkers or genetic variations that can predict the response to a particular therapy. On the other hand, cDx tests are used in conjunction with specific antimicrobial agents to confirm the presence of drug resistance or to monitor therapeutic efficacy.
Fig.1 Stochastic DNA dual-walkers for colorimetric detection of bacteria. (Wang C., et al., 2021)
Point-of-Care (POC) Diagnostics of Infectious Diseases
| Methods |
Pros |
Cons |
| Electrochemical biosensors |
High sensitivity, fast response, and low cost |
Weak stability and susceptibility to interference |
| Fluorescence biosensors |
Rapid response, flexibility, and experimental simplicity |
High fluorescence background |
| SERS-based biosensors |
High sensitivity, well multiplexing capabilities, no photobleaching, and low background |
Limited field of view |
| Colorimetric biosensors |
Simplicity and visualized detection |
Inability to achieve quantitative detection and limited sensitivity |
| Chemiluminiscence biosensors |
High sensitivity, wide linear dynamic ranges, simple instrument |
Time-consuming, and enzyme-dependent |
| SPR-based biosensors |
Label-free and real-time detection |
Bulky equipment and expensive |
| Magnetic biosensors |
Low cost, and high signal-to-noise ratio detection |
Shortage of miniaturized magnetic readout systems |
Our Services
As a leading company in the field of diagnostics development, we offer a comprehensive range of services to support the advancement of infectious disease diagnostics. Our team of expert researchers and scientists works tirelessly to identify novel biomarkers, genetic variations, and molecular targets that are relevant to infectious diseases.
Biomarker Development
- MicroRNAs (miRNAs) biomarkers
- Protein biomarkers
- Nucleic acid biomarkers
- Metabolite biomarkers
- Host immune response biomarkers
Why Choose Us?
We understand that each infectious disease presents unique challenges, and a one-size-fits-all approach may not be optimal. Therefore, our diagnostics development services offer customized solutions tailored to specific infectious diseases or client requirements. This flexibility allows us to address the diverse diagnostic needs in the field of infectious diseases effectively. If our comprehensive range of services has captured your interest, we wholeheartedly urge you to reach out to us without any hesitation.
References
- Wang Chao, et al. "Point-of-care diagnostics for infectious diseases: From methods to devices." Nano Today 37 (2021): 101092.
- Dailey Peter J., Tarek Elbeik, and Mark Holodniy. "Companion and complementary diagnostics for infectious diseases." Expert Review of Molecular Diagnostics 20.6 (2020): 619-636.
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
