Cell therapy has revolutionized the field of medicine, presenting a groundbreaking solution for the treatment of infectious diseases. At our company, we are at the forefront of infectious disease therapeutics, leading the way in developing innovative cell therapy strategies to combat a wide range of infectious pathogens. By partnering with us, you will receive robust support to expedite the progress of your research.
Introduction to Cell Therapy
With the increasing emergence of new pathogens and the growing problem of antibiotic resistance, there is an urgent need for new therapies to address infectious diseases. Cell therapy represents a revolutionary paradigm in contemporary medicine, utilizing living cells as a therapeutic modality for a diverse range of diseases. Unlike conventional drugs that typically focus on symptom relief, cell therapy aims to address the root cause of the disease by harnessing the therapeutic potential of cells.
Fig. 1 CAR T cells targeting infectious diseases. (Seif M, et al., 2018)
How Does Cell Therapy Work?
Cell therapy offers a promising avenue for combating infectious diseases by leveraging the unique capabilities of living cells. This approach involves the administration of therapeutic cells to the patient, which can exert various therapeutic effects, including cell replacement, immunomodulation, and paracrine effects.
Cell Replacement
In some infectious diseases, the patient's cells may be damaged or overwhelmed by the pathogen. The objective of cell therapy is to replace impaired cells with healthy and functional counterparts, restoring normal cellular function and promoting recovery.
Immunomodulation
Atassi and colleagues have synthesized overlapping peptides spanning the entire HC region of BoNT serotype A (BoNT/A). Through thorough analysis, they identified peptides capable of eliciting antibody and T-cell responses in mice, laying the foundation for a potential synthetic vaccine against BoNT intoxication.
Paracrine Effects
The cells used for therapy can secrete bioactive molecules, such as growth factors, cytokines and chemokines, that promote tissue repair, reduce inflammation, and modulate immune responses. By exploiting these paracrine effects, cell therapy can help treat infectious diseases.
Typical Cell Therapy for Infectious Diseases
Cell therapy for infectious diseases includes a variety of approaches. Below are some examples of typical cell therapies.
CAR-T Cell Therapy
Chimeric antigen receptor T (CAR-T) cell therapy encompasses the genetic modification of a patient's own T cells to express a receptor capable of recognizing a particular antigen found on infected cells. This innovative approach has exhibited notable achievements in the treatment of HIV and viral hepatitis.
MSC Therapy
Mesenchymal stem cells (MSCs) are multipotent cells with immunomodulatory properties that can regulate immune responses and inflammation. MSC therapy has been used to treat various infectious diseases, including respiratory infections and viral hepatitis.
NK Cell Therapy
Natural killer (NK) cells are innate immune cells that directly kill infected cells. NK cell therapy involves isolating and expanding NK cells from donor cells and infusing them into the patient. NK cell therapy has been used successfully for HCV and HPV infections.
Our Services
Through meticulous cell selection, a deep understanding of the underlying mechanisms, robust manufacturing processes, and stringent safety considerations, our company offers comprehensive cell therapy development services for infectious diseases. Tailored to different types of infectious diseases and client requirements, we provide diverse cell therapy solutions to accelerate your infectious disease therapeutic development.
Cell Therapy Development Workflow
Types of Cell Therapy and Applicable Infectious Diseases
Types of Cell Therapy
- Stem Cell Therapy
- T-Cell Therapy
- Dendritic Cell Therapy
- Natural Killer (NK) Cell Therapy
- Mesenchymal Stem Cell (MSC) Therapy
- And More
Applicable Infectious Diseases
Why Choose Us?
Questions & Answer
Q: What information do you need to provide for cell therapy development services?
A: We would need information regarding your target infectious disease or pathogen, patient population, cell source preference, timeline, budget, etc.
Q: What is the cycle and price of cell therapy development services?
A: Our service timelines and fees vary depending on the complexity of the project. We can provide a detailed quote based on your specific requirements.
Our company is dedicated to exploring the potential of multiple cell types for the therapies of infectious diseases. If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
References
- Seif M, Einsele H, Löffler J. CAR T cells beyond cancer: hope for immunomodulatory therapy of infectious diseases[J]. Frontiers in immunology, 2019, 10: 2711.
- Khoury M, Cuenca J, Cruz F F, et al. Current status of cell-based therapies for respiratory virus infections: applicability to COVID-19[J]. European respiratory journal, 2020, 55(6).
All of our services and products are intended for preclinical research use
only and cannot be used to diagnose, treat or manage patients.
